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SPYRE THERAPEUTICS INC

93.19

+3.263.63%

Post-market: 93.190.00000.00%19:30 EDT

Volume:1.24M

Turnover:114.72M

Market Cap:8.22B

PE:-46.36

High:95.27

Open:91.16

Low:90.48

Close:89.93

52wk High:110.18

52wk Low:15.86

Shares:88.17M

Float Shares:80.98M

Volume Ratio:0.96

T/O Rate:1.53%

Dividend:- -

Dividend Rate:- -

EPS(TTM):-2.0100

EPS(LYR):-1.9755

ROE:-22.98%

ROA:-19.81%

PB:8.61

PE(LYR):-47.17

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Overview Company News Filings

Spyre Therapeutics CEO Turtle Cameron Disposes of 15,000 Common Shares Worth $1.31 Million

Analysts Offer Insights on Healthcare Companies: Revolution Medicines (RVMD) and Spyre Therapeutics (SYRE)

U.S. Research Roundup-CrowdStrike, Nvidia, Macerich

Top Midday Decliners

MT Newswires Live

Spyre Therapeutics falls -13.2%

Spyre Therapeutics Down over 12%, on Pace for Largest Percent Decrease Since June 2024

U.S. Stocks on the MOVE-Semtech, Donaldson, Meta

Spyre Therapeutics (SYRE) Gets a Buy from LifeSci Capital

Analysts Offer Insights on Healthcare Companies: Solventum Corporation (SOLV), Argenx Se (ARGX) and Spyre Therapeutics (SYRE)

Spyre Therapeutics Reports Phase 2 Skyway RA Data for Spy072 Shows Statistically Significant Benefit vs Placebo

Spyre Therapeutics Shares Down 12.4% Premarket After Co's Experimental Drug Fails to Meet Threshold for Monotherapy Development in Rheumatoid Arthritis

THOMSON REUTERS

Spyre Therapeutics Inc : Btig Cuts Target Price to $121 from $132

THOMSON REUTERS

Stocks to Watch: Intuit, Spyre Therapeutics, Zoom Communications, nCino

Spyre Therapeutics Stock (SYRE) Tumbles 14% in After-Hours – Here’s What Spooked Investors

Spyre Therapeutics Won't Prioritize Rheumatoid Arthritis Monotherapy After Trial

Spyre Therapeutics announces results from RA sub-study of SKYWAY basket trial

Spyre Therapeutics Announces Topline Results from the Rheumatoid Arthritis Sub-Study of the Skyway Phase 2 Trial of Spy072

THOMSON REUTERS

Spyre Therapeutics - Spy072 Well Tolerated with Adverse Event Rates Comparable to Placebo

THOMSON REUTERS

Spyre Therapeutics Inc: Spy072 in Combination with Il17-a/F in Hidradenitis Suppurativa (Hs) in Late 2027 or Early 2028

THOMSON REUTERS

Spyre Therapeutics - Topline Data for Spy072 in Psa and Axspa Expected Q4 2026

THOMSON REUTERS

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Therapeutics CEO Turtle Cameron Disposes of 15,000 Common Shares Worth $1.31 Million","url":"https://stock-news.laohu8.com/highlight/detail?id=2664388298","media":"Reuters","labels":["shareholding","insiderTrades"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2664388298?lang=en_us&edition=fundamental","pubTime":"2026-09-04 09:33","pubTimestamp":1788485613,"startTime":"0","endTime":"0","summary":"Spyre Therapeutics CEO Turtle Cameron disposes of 15,000 common shares worth $1.31 millionSpyre Therapeutics CEO Turtle Cameron sold 15,000 common shares on Sep. 1, 2026 at weighted-average prices of 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halt of its monotherapy RA program.Shares dropped 14% as intraday trading volume rose to over 1.96 million from a daily average of about 1.25 million.Price: 32.20, Change: -7.14, Percent Change: -18.15","market":"sg","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.mtnewswires.com/","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"mtnewswires_news","symbols":["GRML","LFSC","SYRE","BK4082","BK4139","ELMD"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2662474530","title":"Spyre Therapeutics falls 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intraday level since July 7, 2026, when it hit $86.60--Down 15.61% at today's intraday low; largest intraday percent decrease since June 24, 2026, when it fell as much as 15.87%All data as of 10:32:24 AM ETSource: Dow Jones Market Data, FactSet","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://dowjonesnews.com/newdjn/logon.aspx?AL=N","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-2","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["LFSC","BK4139","LENZ","BK4539","SYRE","BK4007"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2662171137","title":"U.S. Stocks on the MOVE-Semtech, Donaldson, 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The company may also accept short-term trade-offs in its business as it looks to boost TurboTax customers, its CFO told The Wall Street Journal. Shares fell 9.8% to $322.57 in after-hours trading on Tuesday.Spyre Therapeutics said it will not prioritize developing one of its drug candidates as a monotherapy for rheumatoid arthritis after results from a trial missed its internal targets. The stock slid 11% to $95.09 after the bell.Zoom Communications issued guidance for third-quarter adjusted earnings per share that missed Wall Street expectations. Shares were down 3.9% at $97.00.NCino projected third-quarter revenue in a range with a midpoint below analyst expectations. 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