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ENGENE HOLDINGS INC

1.94

-0.0400-2.02%

Post-market: 1.91-0.0300-1.55%19:30 EDT

Volume:692.75K

Turnover:1.38M

Market Cap:129.95M

PE:-0.96

High:2.02

Open:2.00

Low:1.93

Close:1.98

52wk High:12.25

52wk Low:1.40

Shares:66.98M

Float Shares:32.73M

Volume Ratio:0.71

T/O Rate:2.12%

Dividend:- -

Dividend Rate:- -

EPS(TTM):-2.0205

EPS(LYR):-2.2947

ROE:-60.50%

ROA:-31.99%

PB:0.56

PE(LYR):-0.85

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Overview Company News Filings

enGene downgraded to Market Perform from Outperform at Citizens

enGene Therapeutics Inc : Piper Sandler Cuts to Neutral From Overweight; Cuts Target Price to $4 From $7

THOMSON REUTERS

enGene downgraded to Neutral from Buy at Guggenheim

enGene announces updated interim results from LEGEND cohort

EnGene Therapeutics Shares Sink After Cancer Study Durability Outcomes Disappoint

enGene reports 43% six-month complete response in Phase 2 LEGEND bladder cancer trial

enGene Therapeutics Inc - Detaimigene Achieves 54% Complete Response at Any Time, 43% at Six Months as of April 21, 2026

THOMSON REUTERS

enGene Therapeutics Inc - 2.4% Experienced Treatment Interruption, 2.4% Discontinuation Due to Adverse Events

THOMSON REUTERS

enGene Therapeutics Inc - 55% Experienced Treatment-Related Adverse Events of Detalimogene, Mostly Mild

THOMSON REUTERS

H.C. Wainwright Keeps Their Buy Rating on enGene Holdings (ENGN)

enGene Holdings Initiated at Buy by WBB Securities

enGene Holdings changes name to enGene Therapeutics as it eyes 2027 launch

BRIEF-Engene Holdings Inc - To Change Name To Engene Therapeutics Inc. Effective April 8, 2026

enGene Holdings Inc - Planned Bla Submission for Detalimogene in Second Half of 2026

THOMSON REUTERS

enGene Holdings Inc - to Change Name to enGene Therapeutics Inc. Effective April 8, 2026

THOMSON REUTERS

enGene Holdings changes name to enGene Therapeutics effective April 8, 2026

Three new option listings and three option delistings on April 6th

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Guggenheim","url":"https://stock-news.laohu8.com/highlight/detail?id=2633087108","media":"TIPRANKS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2633087108?lang=en_us&edition=fundamental","pubTime":"2026-05-08 05:51","pubTimestamp":1778190704,"startTime":"0","endTime":"0","summary":"Guggenheim downgraded enGene (ENGN) to Neutral from Buy. Published first on TheFly – the ultimate source for real-time, market-moving breaking fina...","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/the-fly/engene-downgraded-to-neutral-from-buy-at-guggenheim-thefly-news?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/the-fly/engene-downgraded-to-neutral-from-buy-at-guggenheim-thefly-news?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["ENGN","BK4139"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2633259501","title":"enGene announces updated interim results from LEGEND cohort","url":"https://stock-news.laohu8.com/highlight/detail?id=2633259501","media":"TIPRANKS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2633259501?lang=en_us&edition=fundamental","pubTime":"2026-05-07 22:15","pubTimestamp":1778163338,"startTime":"0","endTime":"0","summary":"enGene (ENGN) Therapeutics reported additional interim results from the pivotal cohort of its ongoing, Phase 2 LEGEND trial of detalimogene vorapla...","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/the-fly/engene-announces-updated-interim-results-from-legend-cohort-thefly-news?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/the-fly/engene-announces-updated-interim-results-from-legend-cohort-thefly-news?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["ENGN","BK4139"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2633407241","title":"EnGene Therapeutics Shares Sink After Cancer Study Durability Outcomes Disappoint","url":"https://stock-news.laohu8.com/highlight/detail?id=2633407241","media":"Dow Jones","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2633407241?lang=en_us&edition=fundamental","pubTime":"2026-05-07 21:15","pubTimestamp":1778159700,"startTime":"0","endTime":"0","summary":"Shares of EnGene Therapeutics plummeted after the company reported disappointing durability outcomes from a Phase 2 trial of its detalimogene voraplasmid drug for bladder cancer patients.The stock fell 73% to $2.36 in premarket trading. Through Wednesday's close, shares had more than doubled over the past 12 months.The company said the estimate for median duration of response was 37.3 weeks. The estimate of the 12-month duration of response was 25%.\"While durability outcomes to date are not what we hoped, these data are preliminary,\" said Chief Executive Ron Cooper.EnGene also said that among the 32 patients who had their first disease assessment after the last data analysis, complete response rates were lower than previously reported results.","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://dowjonesnews.com/newdjn/logon.aspx?AL=N","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-2","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["LENZ","BK4539","ENGN","BK4007","BK4139"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2633145195","title":"enGene reports 43% six-month complete response in Phase 2 LEGEND bladder cancer trial","url":"https://stock-news.laohu8.com/highlight/detail?id=2633145195","media":"Reuters","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2633145195?lang=en_us&edition=fundamental","pubTime":"2026-05-07 19:08","pubTimestamp":1778152128,"startTime":"0","endTime":"0","summary":"enGene Therapeutics reported updated interim results from Phase 2 LEGEND pivotal cohort testing detalimogene in high-risk, BCG-unresponsive non-muscle invasive bladder cancer, with data cut as of April 21, 2026.Responses were seen in more than half of treated patients at some point, with fewer patients remaining cancer-free at later follow-ups, raising durability questions.Disease worsening to more advanced stages remained uncommon, supporting continued use of bladder-sparing approaches for many patients.Safety profile stayed broadly manageable, with most treatment-related side effects mild and few patients stopping therapy due to adverse events.Results will be presented at plenary session during American Urological Association meeting on May 15, 2026, with FDA discussions continuing ahead of potential BLA filing and update expected in second half of 2026.Disclaimer: This news brief was created by Public Technologies  using generative artificial intelligence. While PUBT strives to prov","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260507:nNDL8Pkfw4:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["ENGN","BK4139"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2633514505","title":"enGene Therapeutics Inc - Detaimigene Achieves 54% Complete Response at Any Time, 43% at Six Months as of April 21, 2026","url":"https://stock-news.laohu8.com/highlight/detail?id=2633514505","media":"THOMSON REUTERS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2633514505?lang=en_us&edition=fundamental","pubTime":"2026-05-07 19:00","pubTimestamp":1778151604,"startTime":"0","endTime":"0","summary":null,"market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260507:nTUA8YP0MF:2","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["ENGN","BK4139"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2633145045","title":"enGene Therapeutics Inc - 2.4% Experienced Treatment Interruption, 2.4% Discontinuation Due to Adverse Events","url":"https://stock-news.laohu8.com/highlight/detail?id=2633145045","media":"THOMSON REUTERS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2633145045?lang=en_us&edition=fundamental","pubTime":"2026-05-07 19:00","pubTimestamp":1778151604,"startTime":"0","endTime":"0","summary":null,"market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260507:nTUA8YP0MF:4","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["ENGN","BK4139"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2633145032","title":"enGene Therapeutics Inc - 55% Experienced Treatment-Related Adverse Events of Detalimogene, Mostly Mild","url":"https://stock-news.laohu8.com/highlight/detail?id=2633145032","media":"THOMSON REUTERS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2633145032?lang=en_us&edition=fundamental","pubTime":"2026-05-07 19:00","pubTimestamp":1778151604,"startTime":"0","endTime":"0","summary":null,"market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260507:nTUA8YP0MF:3","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["BK4139","ENGN"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2631750549","title":"H.C. Wainwright Keeps Their Buy Rating on enGene Holdings (ENGN)","url":"https://stock-news.laohu8.com/highlight/detail?id=2631750549","media":"TIPRANKS","labels":["express"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2631750549?lang=en_us&edition=fundamental","pubTime":"2026-04-29 23:55","pubTimestamp":1777478156,"startTime":"0","endTime":"0","summary":"In a report released today, Andres Y. Maldonado from H.C. Wainwright maintained a Buy rating on enGene Holdings, with a price target of $25.00. Acc...","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/blurbs/h-c-wainwright-keeps-their-buy-rating-on-engene-holdings-engn-blurbs-news?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":["rate","earning"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/blurbs/h-c-wainwright-keeps-their-buy-rating-on-engene-holdings-engn-blurbs-news?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"express","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["ENGN"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2627457081","title":"enGene Holdings Initiated at Buy by WBB Securities","url":"https://stock-news.laohu8.com/highlight/detail?id=2627457081","media":"Dow Jones","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2627457081?lang=en_us&edition=fundamental","pubTime":"2026-04-14 01:25","pubTimestamp":1776101100,"startTime":"0","endTime":"0","summary":"Ratings actions from Benzinga: https://www.benzinga.com/quote/ENGN/analyst-ratings \n\n\n \n\n\n  (END) Dow Jones Newswires\n\n\n  April 13, 2026 13:25 ET (17:25 GMT)","market":"other","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://dowjonesnews.com/newdjn/logon.aspx?AL=N","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["ENGN","BK4139"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2626513086","title":"enGene Holdings changes name to enGene Therapeutics as it eyes 2027 launch","url":"https://stock-news.laohu8.com/highlight/detail?id=2626513086","media":"Reuters","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2626513086?lang=en_us&edition=fundamental","pubTime":"2026-04-10 04:03","pubTimestamp":1775765010,"startTime":"0","endTime":"0","summary":"enGene Holdings will rebrand as enGene Therapeutics, signaling a shift toward a potential commercial-stage profile tied to anticipated 2027 approval of lead program detalimogene voraplasmid.Pipeline timeline calls for a biologics license application submission for detalimogene in 2H 2026.Nasdaq tickers remain ENGN for common shares and ENGNW for warrants.Disclaimer: This news brief was created by Public Technologies  using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. enGene Holdings Inc. published the original content used to generate this news brief via EDGAR, the Electronic Data Gathering, Analysis, and Retrieval system operated by the U.S. Securities and Exchange Commission , on April 09, 2026, and is solely responsible for the information contained therein.","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260409:nNDLbXWPVt:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["ENGN","BK4139"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2625309419","title":"BRIEF-Engene Holdings Inc - To Change Name To Engene Therapeutics Inc. Effective April 8, 2026","url":"https://stock-news.laohu8.com/highlight/detail?id=2625309419","media":"Reuters","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2625309419?lang=en_us&edition=fundamental","pubTime":"2026-04-07 20:04","pubTimestamp":1775563463,"startTime":"0","endTime":"0","summary":"BRIEF-Engene Holdings Inc - To Change Name To Engene Therapeutics Inc. Effective April 8, 2026April 7 (Reuters) - enGene Holdings Inc ENGN.O:ENGENE HOLDINGS INC - TO CHANGE NAME TO ENGENE THERAPEUTICS","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260407:nFWN40Q01Z:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["ENGN","ENGNW","BK4139"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2625793063","title":"enGene Holdings Inc - Planned Bla Submission for Detalimogene in Second Half of 2026","url":"https://stock-news.laohu8.com/highlight/detail?id=2625793063","media":"THOMSON REUTERS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2625793063?lang=en_us&edition=fundamental","pubTime":"2026-04-07 20:01","pubTimestamp":1775563294,"startTime":"0","endTime":"0","summary":null,"market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260407:nFWN40Q01Z:2","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["ENGN","ENGNW","BK4139"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2625293056","title":"enGene Holdings Inc - to Change Name to enGene Therapeutics Inc. Effective April 8, 2026","url":"https://stock-news.laohu8.com/highlight/detail?id=2625293056","media":"THOMSON REUTERS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2625293056?lang=en_us&edition=fundamental","pubTime":"2026-04-07 20:01","pubTimestamp":1775563294,"startTime":"0","endTime":"0","summary":null,"market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260407:nFWN40Q01Z:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["BK4139","ENGN"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2625930308","title":"enGene Holdings changes name to enGene Therapeutics effective April 8, 2026","url":"https://stock-news.laohu8.com/highlight/detail?id=2625930308","media":"Reuters","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2625930308?lang=en_us&edition=fundamental","pubTime":"2026-04-07 20:00","pubTimestamp":1775563243,"startTime":"0","endTime":"0","summary":"enGene Holdings will rebrand as enGene Therapeutics, signaling a shift toward a commercial-stage profile ahead of a potential 2027 approval for lead bladder cancer candidate detalimogene voraplasmid.Shares will continue to trade on Nasdaq under ticker ENGN; warrants will remain listed under ENGNW.LEGEND trial remains focused on high-risk non-muscle invasive bladder cancer, including a pivotal cohort in BCG-unresponsive disease with carcinoma in situ.Disclaimer: This news brief was created by Public Technologies  using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. enGene Holdings Inc. published the original content used to generate this news brief via Business Wire  on April 07, 2026, and is solely responsible for the information contained therein.","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260407:nNDL8m4HQd:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4139","ENGN"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2625267191","title":"Three new option listings and three option delistings on April 6th","url":"https://stock-news.laohu8.com/highlight/detail?id=2625267191","media":"TIPRANKS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2625267191?lang=en_us&edition=fundamental","pubTime":"2026-04-06 20:30","pubTimestamp":1775478637,"startTime":"0","endTime":"0","summary":"New option listings for April 6th include enGene Holdings Inc (ENGN), Keel Infrastructure Corp. 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Opt...","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/the-fly/three-new-option-listings-and-three-option-delistings-on-april-6th-thefly-news?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/the-fly/three-new-option-listings-and-three-option-delistings-on-april-6th-thefly-news?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["ENGN","BK4139","KEEL"],"isVideo":false,"video":null,"gpt_icon":0}],"pageSize":20,"totalPage":3,"pageCount":3,"totalSize":57,"code":"91000000","status":"200"}]}}