This article was automatically generated using Dow Jones technology.

Shares of small-cap companies fell Thursday, as the Russell 2000 Index fell 0.1%, and the S&P Small Cap 600 Index was down 0.3%.

Among companies with a market value of $1 billion to $6.7 billion, ACADIA Pharmaceuticals Inc. was the biggest laggard during the session, dropping 13%, followed by shares of Viking Therapeutics Inc., which dropped 12%. Shares of Latigo Biotherapeutics Inc. dropped 11%, uniQure N.V. shares tumbled 10%, and agilon health inc. tumbled 10%.

GRAIL Inc. was the best performer, surging 15%, followed by Korsana Biosciences Inc., which jumped 15%. Securitize Corp. shares surged 15%, Quantum Corp. surged 14%, and shares of CareDx Inc. jumped 13%.

Major U.S. stock indexes closed mixed Thursday as the Nasdaq Composite Index was flat. Meanwhile, the S&P 500 Index was flat, and the Dow Jones Industrial Average fell 0.3%.

Data source: Dow Jones Market Data, FactSet